Surface metal-organic frameworks (SMOFs) are promising platforms for catalysis, yet their structural response to electrochemical bias is often overlooked. We report the potential-driven activation of an N-heterocyclic carbene (NHC)-based SMOF on Au(111) for the hydrogen evolution reaction (HER). This study demonstrates that superior HER performance originates from the SMOF’s ability to dynamically transform into a fluxional active state, providing a strategy for designing adaptive interfacial catalysts.

Signal Amplification By Reversible Exchange (SABRE) delivers rapid and inexpensive NMR signal enhancement using parahydrogen-derived spin order, but biomedical translation requires catalysts that simultaneously deliver high polarization efficiency together with minimal residual metal contamination. Here we introduce a class of single-chain fluorinated Ir-NHC catalysts for SABRE hyperpolarization of [1-¹³C]pyruvate that addresses this longstanding trade-off

Synthesis and Antitumor Activity of Metallates Incorporating Functionalized Azolium Salts

Discover a new class of azolium-derived metallates with remarkable potential as next-generation anticancer agents. Combining sustainable synthesis with exceptional activity against platinum-resistant ovarian cancer, these compounds open exciting new avenues in metal-based therapeutics. Discover more here!